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Conjugated Addition of Bis(oxazolinyl)zinc to Substituted 2-Nitrovinyl Benzenes: An Alternative Synthesis of (.+-.)-Rolipram.

โœ Scribed by Alfredo R. M. Oliveira; Jose A. F. P. Villar; Fabio Simonelli; Rogerio A. Gariani; Celso L. Wosch; Paulo H. G. Zarbin


Publisher
John Wiley and Sons
Year
2007
Weight
28 KB
Volume
38
Category
Article
ISSN
0931-7597

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Trimethylsilyl chloride assisted conjuga
โœ Nobin Terang; Barun K Mehta; H Ila; H Junjappa ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 754 KB

An efficient method for the synthesis of novel 2-methylthio-2-alkyl/aryl-l-nitrocthylenes 2 has been developed via conjugate addition-elimination of organocopper reagents to nitroketene dithioacetal 1 in the presence of TMSCI. The product introethylenes 2 have been further utilized for the synthesis