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Conjugate Addition−Dipolar Cycloaddition Cascade for the Synthesis of Benzo[ a ]quinolizine and Indolo[ a ]quinolizine Scaffolds: Application to the Total Synthesis of (±)-Yohimbenone

✍ Scribed by Stearman, Chad J.; Wilson, Michael; Padwa, Albert


Book ID
120356059
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
286 KB
Volume
74
Category
Article
ISSN
0022-3263

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✍ Steven M. Allin; Christopher I. Thomas; James E. Allard; Kevin Doyle; Mark R. J. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB

## Abstract We present a facile and highly stereoselective approach to the indolo[2,3‐__a__]quinolizine ring system from a readily available, non‐racemic chiral template. We demonstrate the potential for application of this methodology to natural product synthesis through conversion of the template