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Conjugate Addition of Organocopper Reagents to γ-Alkoxybutenolides and Application to the Synthesis of Non-racemic Alkyl Cyclopentenones.

✍ Scribed by Jeremy Robertson; Morgan Menard; Rhonan Ford; Stephen Bell


Publisher
John Wiley and Sons
Year
2005
Weight
29 KB
Volume
36
Category
Article
ISSN
0931-7597

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Trimethylsilyl chloride assisted conjuga
✍ Nobin Terang; Barun K Mehta; H Ila; H Junjappa 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 754 KB

An efficient method for the synthesis of novel 2-methylthio-2-alkyl/aryl-l-nitrocthylenes 2 has been developed via conjugate addition-elimination of organocopper reagents to nitroketene dithioacetal 1 in the presence of TMSCI. The product introethylenes 2 have been further utilized for the synthesis