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Congenital malformations worldwide: A report from the International Clearinghouse for Birth Defects Monitoring Systems

✍ Scribed by Eskes, T.K.A.B.

Book ID
123574321
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
89 KB
Volume
45
Category
Article
ISSN
0301-2115

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## Abstract **BACKGROUND:** Holoprosencephaly (HPE) is a developmental field defect of the brain that results in incomplete separation of the cerebral hemispheres that includes less severe phenotypes, such as arhinencephaly and single median maxillary central incisor. Information on the epidemiolog