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Congenital heart disease in trisomy 21 mosaicism

โœ Scribed by Bruno Marino; Andrea de Zorzi


Book ID
117163979
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
172 KB
Volume
122
Category
Article
ISSN
1097-6833

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The recurrence risk for Down syndrome (DS) is about 1% in case of a previous offspring with trisomy 21 and minimal in case of a de novo (21;21) translocation. We have monitored 1,211 pregnancies in the first and second trimester after a prior occurrence of trisomy 21. Six couples had a trisomy 21 fe