Congenital factor VII deficiency. Clinical and laboratory characteristics of a newly discovered kindred
β Scribed by L. M. KERNOFF; JANE HUGHES; K. W. DENSON
- Book ID
- 114716575
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 468 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1751-5521
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A four-generation 25-member kindred with Factor XI:C deficiency is reported. Factor XI:C levels in heterorygotes varied from 15 to 58940, suggesting that Factor XI:C values for homozygote determination should be less than 15%. The frequency of bleeding was not correlated with Factor XI:C levels in t
M.D.P.); and lmmuno A.G., Vienna, Austria (M.K.) Hereditary factor VII deficiency is a rare autosomal recessive condition, usually associated with normal or reduced levels of a functionally defective molecule. The available means of treating thiscondition in North America presents serious health ri