Methylated CpG Binding Protein 2 (MeCP2) is a nuclear protein named for its ability to selectively recognize methylated DNA. Much attention has been focused on understanding MeCP2 structure and function in the context of its role in Rett syndrome, a severe neurodevelopmental disorder that afflicts o
Conformations of the 8-methylated and unmethylated ribohexamer r(CGCGCG)2
β Scribed by Rao, Shashidhar N.; Kollman, Peter A.
- Book ID
- 127272328
- Publisher
- American Chemical Society
- Year
- 1986
- Tongue
- English
- Weight
- 697 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0002-7863
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The conformation and molecular packing of permethylated /3-D-galactosyl-N-octadecanoyl-D-sphingosine (cerebroside) was determined by X-ray single crystal analysis at 185 K (R = 0.16). The lipid crystallizes in the orthorhombic space group P2~2~2~ with the unit cell dimensions a = 8.03, b ---7.04 and
## Abstract Thiosemicarbazones are having the ability to bind with metal and inhibit the enzyme ribonucleoside diphosphate reductase (RDR), an enzyme which is involved in the synthesis of DNA precursors in the mammalian cells. The title compound Nβmethylβtβ3βmethylβrβ2, cβ6βdiphenylpiperidinβ4βone