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Conformations of dehydrophenylalanine containing peptides Nuclear Overhauser effect study of two acyclic tetrapeptides

โœ Scribed by UMA, K. ;CHAUHAN, V.S. ;KUMAR, ARUN ;BALARAM, P.


Book ID
115098762
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
688 KB
Volume
31
Category
Article
ISSN
0367-8377

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Conformations of dehydrophenylalanine co
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The conformation of an acyclic dehydrophenylalanine ( A'-Phe) containing hexapeptide, Boc-Phe-A'-Phe-Val-Phe-A'-Phe-Val-OMe, has been investigated in CDCl, and (CD,),SO by 270-MHz 'H-nmr. Studies of NH group solvent accessibility and observation of interresidue nuclear Overhauser effects (NOEs) sugg

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The conformation of cyclolinopeptide A [ cyclo(Pro-Pro-Phe-Phe-Leu-Ile-Ile-Leu-Val)], a naturally occurring cyclic nonapeptide has been investigated in dimethylsulfoxide solution by 270 MHz 'H-nmr. A complete assignment of all C"H and NH resonances has been accomplished using two-dimensional correla