𝔖 Bobbio Scriptorium
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Conformations in solution of angiotensin II, and its 1–7 and 1–6 fragments

✍ Scribed by J. A. Cushman; P. K. Mishra; A. A. Bothner-By; M. S. Khosla


Publisher
Wiley (John Wiley & Sons)
Year
1992
Tongue
English
Weight
702 KB
Volume
32
Category
Article
ISSN
0006-3525

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The conformation of 1,6-anhydrolactoase (1) has been investigated by n.m.r. spectroscopy and molecular mechanics calculations. For a solution in D2O, the 1,6-anhydroglucopyranoid ring has a 1C4 conformation, whereas there is a approximately 1:1 equilibrium between the 1C4 and the BO,3 conformations

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## Abstract From ^1^H‐ and ^13^C‐NMR. data, a crown conformation with __trans__ amide bonds is deduced for 1,6‐diaza‐2,7‐cyclodecadione (**1**) in solution. Compound **1** was obtained by reaction of 2‐pyrrolidone with POCl~3~.