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Conformationally Constrained Analogues of Diacylglycerol. 21. A Solid-Phase Method of Synthesis of Diacylglycerol Lactones as a Prelude to a Combinatorial Approach for the Synthesis of Protein Kinase C Isozyme-Specific Ligands

โœ Scribed by Duan, Dehui; Lewin, Nancy E.; Sigano, Dina M.; Blumberg, Peter M.; Marquez, Victor E.

Book ID
127256255
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
94 KB
Volume
47
Category
Article
ISSN
0022-2623

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Conformationally Constrained Analogues o
Conformationally Constrained Analogues of Diacylglycerol. 18. The Incorporation of a Hydroxamate Moiety into Diacylglycerol-Lactones Reduces Lipophilicity and Helps Discriminate between sn-1 and sn-2 Binding Modes to Protein Kinase C (PK-C). Implications for Isozyme Specificity.
โœ Lee, Jeewoo; Han, Kee-Chung; Kang, Ji-Hye; Pearce, Larry L.; Lewin, Nancy E.; Ya ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 11 KB