Conformational study on 2-oxa-bicyclo[3.3.0]octan-3-ones. configurational assignments in carbocyclic five-membered rings by 1H-NMR.

Configurational 1H NMR study of opticall

Configurational 1H NMR study of optically active 7-(1-phenylethyl)-2-oxa-7-azabicyclo[3.2.0]heptan-6-one derivatives using Pirkle’s alcohols and a chiral shift reagent

✍ Cirilo García-Martínez; Yoichi Taguchi; Akihiro Oishi; Kikuko Hayamizu 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 340 KB

Four novel stereoisomers of 7-(1-phenylethyl)-2-oxa-7-azabicyclo[3.2.0]heptan-6-one were prepared under high pressure from [2 ] 2] cycloaddition of the pure enantiomers of 1-phenylethyl isocyanate and 2,3dihydrofuran. Their conformational preferences in solution and the absolute conÐgurations of the