✦ LIBER ✦
Conformational study of diastereomers. V—assignment of RR and RS relative configurations to 2,2,6,6-tetramethyl-5-phenyl-3-heptanol by proton n.m.r.
✍ Scribed by C. Alvarez Ibarra; M. S. Arias Perez; F. Fernandez Gonzalez; M. Rico Sarompas
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 308 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0749-1581
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✦ Synopsis
Abstract
Assignment of RR and RS configurations to 2,2,6,6‐tetramethyl‐5‐phenyl‐3‐heptanol diastereomers has been carried out through an analysis of the observed values for vicinal coupling constants of both isomers and their conformational distribution. The latter was previously estimated from steric interaction energies between groups. Since the RR isomer is monoconformational its magnetic parameters can be used to carry out conformational analysis of related acyclic compounds.