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Conformational study of cyclo(1,5)-Ac-Pen-Arg-Gly-Asp-Cys-NH2 in water by NMR and molecular dynamics

✍ Scribed by Teruna J. Siahaan; Soma Chakrabarti; David Vander Velde


Book ID
115765304
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
361 KB
Volume
187
Category
Article
ISSN
0006-291X

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Solution Conformation of [D-Pen2,D-Pen5]
✍ Martin Gußmann; Rolf Borsdorf; Hans–JΓΆrg Hofmann πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 457 KB

The solution conformation of [D-Pen2, D-Pen5] enkephalin (DPDPE), a highly potent delta-selective opioid agonist, was examined by means of NMR, molecular mechanics and molecular dynamics methods. The structural information in the solvent water was obtained employing one- and two-dimensional methods