✦ LIBER ✦

Conformational study of chiral acyclic ketones by 1H and 13C NMR. I. (±)-2,2,6,6-tetramethyl-5-phenylheptan-3-one

✍ Scribed by C. Alvarez-Ibarra; M. S. Arias-Pérez; A de Andrés; J. L. Balcázar

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 886 KB
Volume: 24
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260240703

No coin nor oath required. For personal study only.

✦ Synopsis

The conformational analysis of a chiral acyclic ketone with one asymmetric carbon, ( f )-2,2,6,64etramethyl-

S-phenylheptan-3-one, has been achieved for the first time by means of an x-ray diffraction study and the analysis of 'H-lH and 13C-'H geminal and vicinal coupling constants and "C-'H direct coupling constants.

The application of the Dnrette-Horton, Pachler and Altona empirical equations supports the hypothesis of a marked predominance in solution crf the conformation observed in the solid state.

📜 SIMILAR VOLUMES

The conformation of t-butyl 2-methoxy-5,

The conformation of t-butyl 2-methoxy-5, 6-dihydro-2 H-pyran-6-carboxylates and 6,6′- disubstituted 2-methoxy-5,6-dihydro-2H-pyran derivatives on the basis of 1H and 13 C NMR spectra

✍ Marek Chmielewski; Janusz Jurczak; Aleksander Zamojski; Halina Adamowicz 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 474 KB

## Abstract The ^1^H and ^13^C NMR spectra of __trans__‐ and __cis__‐__tert__‐butyl 2‐methoxy‐5,6‐dihydro‐2__H__‐pyran‐6‐carboxylates (1 and 2) and 6,6′‐disubstituted 2‐methoxy‐5,6‐dihydro‐2__H__‐pyrans (3‐7) have been recorded. HH and CH coupling constants are discussed in terms of the ^1^H~6~⇄^6^

Carbon-13 NMR Studies. 127—13C and 2H NM

Carbon-13 NMR Studies. 127—13C and 2H NMR investigations of 1H/2H exchange in isomeric tricyclic [5.2.1.0] and [5.3.1.0] ketones

✍ Jeffrey L. Jurlina; Hemant A. Patel; Sriyawathie Peiris; J. B. Stothers 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 584 KB

Under strongly basic conditions (f-BuO-/f-BuOD at 185 "C), the 9,9-dirnethyltricycl0[5.2.1.0~~~]-and -[5.2.1.0'\*5]decan-8-ones and the homologous [5.3.1.0]undecanones undergo multi-site 'H/'H exchange. The total 2H uptake was monitored by mass spectrometry, while the individual sites of exchange we

Conformational analysis. XXVII—A 1H and

Conformational analysis. XXVII—A 1H and 13C NMR conformational study of cis- and trans-annelated 2-p-nitrophenyl-4,5- and -5,6-tetramethyleneper-hydro- and 2-p-chlorophenyl-4,5- and -5,6-tetramethylenedihydro-1,3-oxazines

✍ Kalevi Pihlaja; Jorma Mattinen; Gábor Bernáth; Ferenc Fülöp 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB

1H, 13C and 31P NMR studies of the stere

1H, 13C and 31P NMR studies of the stereochemistry of chiral (4R, 6R)-2-substituted-1,3,2-dioxaphosphorinanes

✍ G. Szalontai; J. Bakos; I. Tóth; B. Heil; I. Pelczer; P. Sohár 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 841 KB

Synthesis and complete assignment of the

Synthesis and complete assignment of the 1H and 13C NMR spectra of 6-substituted and 2,6-disubstituted pyridazin-3(2H)-ones

✍ Pedro Besada; Tamara Costas; Noemi Vila; Carla Chessa; Carmen Terán 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 116 KB

## Abstract Several pyridazin‐3(2__H__)‐one derivatives were synthesized starting from alkyl furans using oxidation with singlet oxygen to give 4‐methoxy or 4‐hydroxybutenolides, key intermediates of the synthetic strategy followed. For all pyridazinones reported, a complete assignment of the ^1^H

1H and 13C NMR spectral studies of C-2 s

1H and 13C NMR spectral studies of C-2 substituted isomeric exo- and endo-5-methyl-bicyclo[3.2.1]octane-6,8-diones

✍ T. R. Kasturi; S. Madhava Reddy; Parvathi S. Murthy 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 939 KB

## Abstract A detailed analysis of the ^1^H and ^13^C NMR spectra of C‐2 aryl and alkyl/desalkyl substituted isomeric __exo__‐ and __endo__‐5‐methylbicyclo[3.2.1]octane‐6,8‐diones is presented. The chemical shift of the C‐5 angular methyl, the C‐2 alkyl/olefinic (C‐10)/C‐2 methine protons, the arom