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Conformational studies on B/C-cis- and B/C-trans-morphinan derivatives

✍ Scribed by Zoltán Szabó; János Marton; Sándor Hosztafi

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
303 KB
Volume
33
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

An unambiguous structural differentiation of B/C‐cis‐ and B/C‐trans‐morphinan derivatives (thebainone‐A and β‐thebainone‐A and their 7,8‐dihydro derivatives) is provided. The structures were confirmed by NOE difference spectroscopy and selective 2D J‐INEPT experiments. In addition, full a priori ^1^H and ^13^C NMR assignments of the isomeric pairs studied are presented.

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