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Conformational Studies of Stereoisomeric Tetrols Derived from syn- and anti -Dibenzo[ a,l ]pyrene Diol Epoxides

✍ Scribed by Jankowiak, Ryszard; Ariese, Freek; Zamzow, Dan; Luch, Andreas; Kroth, Heiko; Seidel, Albrecht; Small, Gerald J.


Book ID
127138742
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
320 KB
Volume
10
Category
Article
ISSN
0893-228X

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## Abstract The polycyclic aromatic hydrocarbons (PAHs) dibenzo[__a,l__]pyrene (DBP) and benzo[__a__]pyrene (BP) are environmental contaminants and potent carcinogens. DBP is several orders of magnitude more mutagenic/carcinogenic than BP. This can be ascribed to differences in DNA binding efficien