Conformational, steric and electronic effects on the site- and chemoselectivity of the metal-catalyzed reaction of N-bis(trimethylsilyl)methyl, N-(2-indolyl)methyl α-diazoamides
✍ Scribed by Zhang, Bao; Wee, Andrew G. H.
- Book ID
- 118176536
- Publisher
- Royal Society of Chemistry
- Year
- 2012
- Tongue
- English
- Weight
- 336 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1477-0520
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The N-bis(trimethysilyl)methyl (N-BTMSM) group is effective for conformational control about the amide N C(O) bond in tertiary diazoamides; metallocarbenoid C-H insertion reaction occurs only at the other N-'alkyl' unit. In C a -unbranched diazoamides, the inherent electronic effects of the N-'alkyl