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Conformational requirements for antibody recognition of fluphenazine and the thermodynamics of the binding processes

✍ Scribed by F.J. Rowell; K. Dixon; S.M. Hui

Book ID
119088750
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
410 KB
Volume
17
Category
Article
ISSN
0161-5890

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## Abstract We analyzed the binding of the 7C8 antibody to the chloramphenicol phosphonate antigensβ€”one containing a trifluoroacetyl group (CP‐F) and the other containing an acetyl group (CP‐H)β€”by using isothermal titration calorimetry (ITC). The thermodynamic difference due to the substitution of