Conformational Preferences of Neurotransmitters: Ephedrine and Its Diastereoisomer, Pseudoephedrine
β Scribed by Butz, Patrick; Kroemer, Romano T.; Macleod, Neil A.; Simons, John P.
- Book ID
- 126018954
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 119 KB
- Volume
- 105
- Category
- Article
- ISSN
- 1089-5639
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The conformational constraints imposed by 7-1actams in peptides have been studied using valence force field energy calculations and flexible geometry maps. It has been found that while cyclisation restrains the ~u of the lactam, non-bonded interactions contribute to the constraints on ~0 of the lact