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Conformational preference in 8-alkyl-8, 9,10, 11-tetrahydro-7H-cycloocta[dedenaphthalene-9-ones

โœ Scribed by Toshihiro Kamada; Osamu Yamamoto


Book ID
104243843
Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
240 KB
Volume
18
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Compared to cycloalkanes, little is known about the stereochemistry of pericyclic naphthalenes , particularly compounds of medium-sized rings. l-4 During our studies of conformations of the peri-ring system 394 in some derivatives of


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The ~, ~x'-annelation of the enamine of 1,3-dihydro-2-phenalenone with methyl ct-(bromomethyl)acrylate affords an aromatic bieyclie framework, methyl 8,9,10,1 l-telrahydro-7,11-methano-12-keto-TH-cycloocta(de)naphthalene-9-endo-carboxylate having the ester function positioned over the aromatic ring.