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Conformational polymorphism in aripiprazole: Preparation, stability and structure of five modifications

โœ Scribed by Braun, Doris E. (author);Gelbrich, Thomas (author);Kahlenberg, Volker (author);Tessadri, Richard (author);Wieser, Josef (author);Griesser, Ulrich J. (author)

Publisher
John Wiley and Sons Inc.
Year
2009
Tongue
English
Weight
814 KB
Volume
98
Category
Article
ISSN
0022-3549

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Conformational polymorphism in aripipraz
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## Abstract The prediction of changes in protein stability and structure resulting from single amino acid substitutions is both a fundamental test of macromolecular modeling methodology and an important current problem as high throughput sequencing reveals sequence polymorphisms at an increasing ra