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Conformational Mapping of Amyloid Peptides from the Putative Neurotoxic 25-35 Region

โœ Scribed by I. Laczko; S. Holly; Z. Konya; K. Soos; J.L. Varga; M. Hollosi; B. Penke


Book ID
115575665
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
353 KB
Volume
205
Category
Article
ISSN
0006-291X

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โœ C. Arias; I. Arrieta; R. Tapia ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 554 KB

P-Amyloid protein (PAP) has been frequently associated with the neuropathology of Alzheimer's disease (AD), although the mechanisms by which it can induce neurodegeneration are still unknown. Some studies in hippocampal cultured neurons suggest that PAP, particularly its fragment 25-35, may induce n