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Conformational homogeneity in solution of 14-membehed macrolide antibiotics as evidenced by 13C NMR spectroscopy

✍ Scribed by Satoshi Ōmura; András Neszmélyi; Malick Sangaré; Gabor Lukacs

Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
227 KB
Volume
16
Category
Article
ISSN
0040-4039

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## Abstract A complete assignment of the ^1^H and ^13^C NMR spectra of roxithromycin in deuteriochloroform, methanol‐__d__~4~ and D~2~O was made using different two‐dimensional (2D) chemical shift correlation methods. The coupling constants observed by ^1^H NMR and the NOEs show that the predominan