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Conformational Flexibility and Peptide Interaction of the Translocation ATPase SecA

✍ Scribed by Jochen Zimmer; Tom A. Rapoport


Book ID
116664321
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
610 KB
Volume
394
Category
Article
ISSN
0022-2836

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## Abstract Bacteria employ the SecA motor protein to push unfolded proteins across the cytoplasmic membrane through the SecY protein‐conducting channel complex. The crystal structure of the SecA–SecY complex shows that the intramolecular regulator of ATPase1 (IRA1) SecA domain, made up of two heli