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Conformational equilibria of TADDOL-s in solution investigated by vibrational circular dichroism

โœ Scribed by Cornelia Uncuta; Emeric Bartha; Dragos Gherase; Florina Teodorescu; Constantin Draghici; Dominique Cavagnat; Nicolas Daugey; Daniel Liotard; Thierry Buffeteau


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
279 KB
Volume
22
Category
Article
ISSN
0899-0042

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## Abstract The vibrational absorption and vibrational circular dichroism (VCD) spectra of melittin in D~2~O solutions at different pH values, different salt concentrations, or different 2,2,2โ€trifluoroethanol (TFE) concentrations are recorded in the amide Iโ€ฒ (1850โ€“1600 cm^โˆ’1^) region. Two models a

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## Abstract Pexiganan (Glyโ€“Ileโ€“Glyโ€“Lysโ€“Pheโ€“Leuโ€“Lysโ€“Lysโ€“Alaโ€“Lysโ€“Lysโ€“Pheโ€“Glyโ€“Lysโ€“Alaโ€“Pheโ€“Valโ€“Lysโ€“Ileโ€“Leuโ€“Lysโ€“Lys), a 22 amino acid peptide, is an analogue of the magainin family of antimicrobial peptides present in the skin of the African clawed frog. Conformational analysis of pexiganan was carried

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Vibrational-circular-dichroism (VCD) studies of the solution conformations of three 2,2'-substituted biphenyls are reported. Biphenyls with only two substituents at the peri-position normally show rotation about their central axis of chirality at room temperature in solution. We previously found no