Conformational effects in the opening of cis/trans 1,4-dialkyl substituted 1,2-cyclohexene epoxides with acetic acid

Steric effects in the ene reaction.: The

Steric effects in the ene reaction.: The reaction of benzyne with cis-and trans-2-methylbut-1-en-1-yl acetates

✍ H.H. Wasserman; L.S. Keller 📂 Article 📅 1974 🏛 Elsevier Science 🌐 French ⚖ 201 KB

In previous studies on the stereochemistry of benzyne addition to enol ethers and acetates we observed both stereoselective 2+2 cycloaddition and ene reaction. 1 In each series, however, we found that the proportion of ene product relative to cycloaddition was significantly larger with the trans-is