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Conformational dynamics of 4-aryl-1,4-dihydropyridine calcium channel antagonists. 1. Quantitation of C4-C1′ bond rotational barriers

✍ Scribed by Robert B. Palmer; Niels H. Andersen


Book ID
103397027
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
888 KB
Volume
52
Category
Article
ISSN
0040-4020

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📜 SIMILAR VOLUMES


Conformational Preferences and Dynamics
✍ Robert B. Palmer; Tina M. Andro; Nicholas R. Natale; Niels H. Andersen 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 1011 KB

A series of 14 4-(3',5'-disubstituted isoxazolyl)-1,4-dihydropyridine calcium channel antagonists were examined using variable-temperature proton nuclear magnetic resonance spectroscopy and nuclear Overhauser effect (NOE) experiments. Two of these compounds, the 1,4-dihydro-2,6-dimethyl-4-[ S-methyl