Studies of unfolded and partially folded proteins provide important insight into the initiation and process of protein folding. This review focuses on the use of nmr in characterization of ensembles of proteins that model the early stages of folding. Analysis of an ensemble includes description of t
✦ LIBER ✦
Conformational Dynamics and Ensembles in Protein Folding
✍ Scribed by Muñoz, Victor
- Book ID
- 115450973
- Publisher
- Annual Reviews
- Year
- 2007
- Tongue
- English
- Weight
- 371 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1056-8700
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## Abstract An important, but often neglected, contribution to the thermodynamics of protein folding is the loss of entropy that results from restricting the number of accessible side‐chain conformers in the native structure. Conformational entropy changes can be found by comparing the number of ac
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