Conformational distributions of N-acetyl-L-proline N-methylamide in CDCl3 solution studied by NMR and IR spectra
β Scribed by Minoru Akiyama; Toshiaki Ohtani; Yukari Furuta; Eiji Watanabe
- Book ID
- 108008939
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 585 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1386-1425
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π SIMILAR VOLUMES
NH stretching bands of N-acetyl-(glycine, L-alanine, L-leucine)-W-methylamides in dilute chloroform solution have shown that these dipeptides are present as a mixture of intramolecularly hydrogen-bonded five-membered ring species and nonhydrogen bonded species. Integrated absorption intensity measur
The 'H-nmr studies were extensively carried out to elucidate preferred conformations of dipeptides CH,C\*O-X-NHCH,, with X = Abu, oval, and Val in various solvents. The vicinal 'H--'H coupling constants for the NH-CnH moiety and those around the C"-Cp bond in the articulated side chain provided the
## Abstract NβAcetylβprolineβmethylamide (APMA) was synthesized by the mixed anhydride method and investigated by IR. spectroscopy and chemical relaxation measurements. The temperatureβinduced variation of the IR. absorption bands of the internally hydrogen bonded (b) and of the extended, unbonded
## Synopsis Concentration and temperature dependences of the 'H nmr spectra of N-acetyl-L-proline N-methylamide were observed in various solvents [CCld, CDCl:j, (CD:j)&O, (CD:JaSO, H&, and D20]. The fraction of the cis isomer (with respect to the bond between the acetyl carbonyl carbon and prolyl