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Conformational changes of aspartate induced by high salt concentrations

✍ Scribed by Gennaro Esposito; Antonio Donesi; Piero A. Temussi


Publisher
Elsevier Science
Year
1982
Weight
403 KB
Volume
24
Category
Article
ISSN
0378-4487

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✦ Synopsis


The conformational changes of aspartate induced by increasing ionic strength were investigated by means of NMR spectroscopy. The effects of Li, Na, K and Cs chlorides in basic solutions show a relative stabilization of the two conformers with gauche carboxylates at the expense of the anti conformer. A significant quantitative difference was found between Na+ and K+. The changes observed in neutral solutions, although larger than those in basic solutions, are dominated by the zwitterion interaction.


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