Conformational changes of aspartate induced by high salt concentrations
β Scribed by Gennaro Esposito; Antonio Donesi; Piero A. Temussi
- Publisher
- Elsevier Science
- Year
- 1982
- Weight
- 403 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0378-4487
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β¦ Synopsis
The conformational changes of aspartate induced by increasing ionic strength were investigated by means of NMR spectroscopy. The effects of Li, Na, K and Cs chlorides in basic solutions show a relative stabilization of the two conformers with gauche carboxylates at the expense of the anti conformer. A significant quantitative difference was found between Na+ and K+. The changes observed in neutral solutions, although larger than those in basic solutions, are dominated by the zwitterion interaction.
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