G, and G,, respectively, activate and inhibit the enzyme adenylyl cyclase. Regulation of adenylyl cycldse by the heterotrimeric G, and G, proteins requires the dissociation of GDP and binding of GTP to the a, or a, subunit. The 0-y subunit complex of G, and G, functions, in part, to inhibit GDP diss
✦ LIBER ✦
Conformational Changes in the Amino-Terminal Helix of the G Protein α i1 Following Dissociation From Gβγ Subunit and Activation
✍ Scribed by Medkova, Martina; Preininger, Anita M.; Yu, Nan-Jun; Hubbell, Wayne L.; Hamm, Heidi E.
- Book ID
- 127031910
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 399 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0006-2960
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