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Conformational Changes in Subunit A of Cholera Toxin Following the Binding of Ganglioside to Subunit B

✍ Scribed by Simon VAN HEYNINGEN

Book ID
115120977
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
518 KB
Volume
122
Category
Article
ISSN
1432-1327

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✍ Sarah Spiegel πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 591 KB

The use of the B subunit of cholera toxin, a protein that binds specifically to ganglioside GM 1, has provided a new paradigm for studying physiological functions of ganglioside GMl . The B subunit inhibited the growth of rat glioma C6 cells that had been pretreated with ganglioside GM1. In some pre