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Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors

✍ Scribed by Stephen Suresh; Jerome C Bressi; Kevin J Kennedy; Christophe L.M.J Verlinde; Michael H Gelb; Wim G.J Hol

Book ID
115630970
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
970 KB
Volume
309
Category
Article
ISSN
0022-2836

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The antibodies specific to an inactive glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Bacillus stearothermophilus prepared by the treatment of the tetrameric holoenzyme with glutaraldehyde were obtained. They were purified from the pool of polyclonal rabbit antibodies to GAPDH with the use of