Conformational changes in chromatin from density inhibited WI-38 fibroblasts stimulated to proliferate
β Scribed by Claudio Nicolini; Renato Baserga
- Book ID
- 105651949
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 1008 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0940-5437
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π SIMILAR VOLUMES
## Abstract Previous work from this laboratory (Rovera and Baserga, 1971) has shown that, when densityβinhibited WIβ38 human diploid fibroblasts are stimulated to proliferate by a change of medium, the synthesis of nuclear acidic proteins increases within 30 minutes after stimulation; several hours
## Abstract In quiescent confluent monolayers of WIβ38 cells, the specific activity of the tRNA methyltransferases falls to 20% of the level found in log phase cells. When the resting cells are stimulated to proliferate by a change to fresh medium, the enzymes show a rapid rise in specific activity