Tryptophan side chain conformers monitor
β
Olivier Julien; Guoli Wang; Abel Jonckheer; Yves Engelborghs; Brian D. Sykes
π
Article
π
2011
π
John Wiley and Sons
π
English
β 829 KB
## Abstract We have inserted a tryptophan (F77W) in the core of the regulatory domain of cardiac troponin C (cNTnC), and previously determined the structure of this mutant with and without the cosolvent trifluoroethanol (TFE). Interestingly, the orientations of the indole side chain of the Trp are