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Conformational Changes in a Photosensory LOV Domain Monitored by Time-Resolved NMR Spectroscopy

✍ Scribed by Harper, Shannon M.; Neil, Lori C.; Day, Iain J.; Hore, P. J.; Gardner, Kevin H.


Book ID
126413711
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
71 KB
Volume
126
Category
Article
ISSN
0002-7863

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## Abstract We have inserted a tryptophan (F77W) in the core of the regulatory domain of cardiac troponin C (cNTnC), and previously determined the structure of this mutant with and without the cosolvent trifluoroethanol (TFE). Interestingly, the orientations of the indole side chain of the Trp are