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Conformational Changes and Free Energies in a Proline Isomerase

✍ Scribed by Papaleo, Elena; Sutto, Ludovico; Gervasio, Francesco Luigi; Lindorff-Larsen, Kresten


Book ID
126795598
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
724 KB
Volume
10
Category
Article
ISSN
1549-9618

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Conformational analysis. Part 16 Conform
✍ Raymond J. Abraham; Craig J. Medforth; Paul E. Smith πŸ“‚ Article πŸ“… 1991 πŸ› Springer Netherlands 🌐 English βš– 518 KB

The conformational free energies (-AG Β°) of a number of 4-substituted piperidines and piperidinium salts have been determined by the J-value method. For the 4-substituted piperidines (R = Me, Phenyl, CO2Et, Br, OH, F) the relative conformer energies are almost identical to those of the analogous cyc