Conformational and Dynamical Properties of the Isolated, Three-Dimensional Single- and Double-Tethered Polymer Chain on an Infinite Surface
✍ Scribed by Miriam Fritsche; Dieter W. Heermann; Mariana Dutra; Claudette E. Cordeiro
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 416 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1022-1344
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✦ Synopsis
Abstract
By Monte Carlo simulations we provide insight into the isolated single‐ and double‐tethered (ST and DT) polymer chain attached to an impenetrable surface to elucidate open theoretical questions and guide future experiments investigating the impact of tethering on the genome packaging by concurrent visualisation of multiple loci along the chromosome(s). In the models, either one or both ends (at a grafting distance d) are fixed or the ST and DT chain are “annealed” by permitting the anchor(s) to diffuse laterally along the surface. We analyse chain self‐entanglement, intrachain segment correlations, the relationship between mean square physical distance and corresponding contour length and provide the first report on the diffusion behaviour.
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