𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conformational analysis of β and γ-lactam antibiotics

✍ Scribed by J Lamotte; G Dive; JM Ghuysen

Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
709 KB
Volume
26
Category
Article
ISSN
0223-5234

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Theoretical studies on β-lactam antibiot
Theoretical studies on β-lactam antibiotics. IV. Conformational analysis of novel β-lactam antibiotics and the binding specificities of crosslinking enzyme(s) and β-lactamases
✍ T. K. Vasudevan; V. S. R. Rao 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 609 KB

## Abstract Conformational‐energy calculations were carried out on the new family of β‐lactam antibiotics (viz., thienamycin, PS‐5, 1‐oxa‐ and 1‐thiapenems, and their close analogs); these exhibit broad‐spectrum antibacterial activity and stability towards β‐lactamase‐producing strains. The bicycli

Monocyclic β-lactam antibiotics
Monocyclic β-lactam antibiotics
✍ Christopher M. Cimarusti; Richard B. Sykes 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 958 KB

reevaluation of beta-lactam bond deformation as a criterion for a penicillin-like mode-of-action. ## 11. MECHANISM OF ACTION The mechanism of action of the naturally-occurring monobactams was examined at an early They were shown to interact with certain of the penicillin-binding proteins (PBP's) o

Conformational Analysis of β-Lactam-Cont
Conformational Analysis of β-Lactam-Containing Ferrocene Peptides
✍ Veronika Kovač; Katarina Radolović; Ivan Habuš; Daniel Siebler; Katja Heinze; Vl 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 942 KB

The homochiral 3-amino-1-(4-methoxyphenyl)-4-phenyl-βlactam (ϵ Alm) was conjugated with Boc-Ala to give Ala-Alm (9) after Boc deprotection (Boc = tert-butoxycarbonyl, Ala = alanine). Coupling of Fc-COOH (1) and Boc-Fca (10) with "dipeptide" 9 resulted in the formation of Fc-CO-Ala-Alm ( ) and the tr