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Conformational Analysis of Thioflavin T Bound to the Surface of Amyloid Fibrils

✍ Scribed by Robbins, Kevin J.; Liu, Gai; Selmani, Veli; Lazo, Noel D.


Book ID
118221853
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
872 KB
Volume
28
Category
Article
ISSN
0743-7463

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## ABSTRACT Abnormal fibrillization of amyloidogenic peptides/proteins has been linked to various neurodegenerative diseases such as Alzheimer's and Parkinson's disease as well as with type‐II diabetes mellitus. The kinetics of protein fibrillization is commonly studied by using a fluorescent dye T