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Conformational Analysis of the Neuropeptide Y Fragment NPY(18–36) by 1H-NMR and Computer Simulationa

✍ Scribed by R. D. FEINSTEIN; M. SPICER; J. BOUBLIK; J. P. TAULANE; J. RIVIER; M. BROWN; M. GOODMAN

Book ID
119865332
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
134 KB
Volume
611
Category
Article
ISSN
0890-6564

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Conformational properties of the proline
Conformational properties of the proline region of porcine neuropeptide Y by CD and 1H-NMR spectroscopy
✍ Shao Song Chu; David Vander Velde; David Shobe; Preeti Balse; Michael B. Doughty 📂 Article 📅 1995 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 912 KB

We synthesized porcine neuropeptide Y (pNPY) N-terminalfragments by solid-phase synthesis techniques and analyzed them for solution conformational properties by CD and 'H-nmr spectroscopy. The analogues pNPYI-, and pNPYI-,, displayed CD spectra indicative of random structures and showed no evidence