Conformational analysis of nucleoside analogs of six-membered heterocycles containing oxygen and/or sulfur
β Scribed by Walter A. Szarek; Dolatrai M. Vyas; Barbara Achmatowicz
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 211 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The conformational analysis of three unconstrained eight-membered heterocycles (1, has been carried out. The relative energies of all possible conformations were calculated and their appropriately weighted contributions yielded good simulations of the 1H NMR spectra of these compounds.
## Abstract Theoretical and experimental ^2^__J__~HH~ coupling constants for sixβmembered rings containing oxygen or sulfur atoms were studied to investigate whether the ^2^__J__~HH~ coupling constant can be used for stereoelectronic studies in heterocyclohexanes, instead of ^1^__J__~CH~, because i