Conformational analysis of an opioid peptide in solvent media that mimic cytoplasm viscosity

Conformation–activity relationship of a

Conformation–activity relationship of a novel peptide antibiotic: Structural characterization of dermaseptin DS 01 in media that mimic the membrane environment

✍ M. A. Castiglione-Morelli; Pierluigi Cristinziano; Antonietta Pepe; Piero A. Tem 📂 Article 📅 2005 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 332 KB 👁 1 views

## Abstract Dermaseptins, small polycationic peptides synthesized by amphibians, exert a lytic action on bacteria, protozoa, yeast, and filamentous fungi at micromolar concentrations, but unlike polylysines, show little hemolytic activity. Dermaseptins S are active only against bacteria and form ag