Conformational analysis of 1α,25-dihydroxyvitamin D3 by nuclear magnetic resonance
✍ Scribed by Tadashi Eguchi; Nobuo Ikekawa
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 634 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0045-2068
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In this communication we describe the synthesis of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\) - \(3 \beta\)-bromoacetate \(\left[1,25(\mathrm{OH})_{2}-\mathrm{BE}\right]\), an analog of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\left[1,25(\mathrm{OH})_{2} \mathrm{D}_{3}\right]\), a
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The active form of vitamin D~3~, 1,25(OH)~2~D~3~, is known, besides its classical effects on calcium and bone, for its pronounced immunomodulatory effects that are exerted both on the antigen‐presenting cell level as well as directly on the T lymphocyte level. In animal models, these im