Conformational analysis by NMR spectroscopy of 2′-deoxy-2′-C-alkylnucleosides: Building blocks of new antisense fragments
✍ Scribed by D. O. Cicero; A. M. Iribarren; R. Bazzo
- Book ID
- 113000923
- Publisher
- Springer Vienna
- Year
- 1994
- Tongue
- English
- Weight
- 600 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0937-9347
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Structural and Conformational Analysis by lH NMR and 13C NMR of a New Angiotensin I Converting Enzyme Inhibitor, the tert-Butylamine Salt of (2S)-2-[ (1S)-l-Carbethoxybutylamino]-loxopropyl-(2S,3aSJaS) perhydroindole-2-carboxylic acid (Perindopril)
## Abstract The ^1^H, ^13^C and ^15^N NMR studies have shown that the __E__ and __Z__ isomers of pyrrole‐2‐carbaldehyde oxime adopt preferable conformation with the __syn__ orientation of the oxime group with respect to the pyrrole ring. The __syn__ conformation of __E__ and __Z__ isomers of pyrrol