Conformational Analysis and Rotational Barriers of Alkyl- and Phenyl-Substituted Urea Derivatives
β Scribed by Bryantsev, Vyacheslav S.; Firman, Timothy K.; Hay, Benjamin P.
- Book ID
- 119958250
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 602 KB
- Volume
- 109
- Category
- Article
- ISSN
- 1089-5639
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π SIMILAR VOLUMES
The conformati ons and the rotational barriers of the 2-substituted 1,3-diphenylallylanions lb-g (Tab.2) have been determined. Increasing size of the substituents leads tomore exo,endo-and endo,endo-conformers at the cost of the exo,exo-species. This trend is connected with decreasing AG\*-values of
Rotational barriers about the CΓN bonds of several N-acyl-N-methyl-a-amino acids and their esters R3COΓ N(R4)ΓCR1R2ΓCOOR5, and also N-Boc-protected dipeptides, were determined and the steric e β ects caused by the substituents R1-R5 are discussed by comparing them with the results of MM3 calculations