Conformational analyses of 0-4,0-6-branching tri-D-glucopyranosides; influence of 0-4 linked residues on solution conformations about C5C6 bonds at (1–6)-linkages

✍ Scribed by Yoshihiro Nishida; Hiroshi Hori; Hiroshi Ohrui; Hiroshi Meguro; Jun Uzawa; Dirk Reimer; Volker Sinnwell; Hans Paulsen

• Book ID: 104216647
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 271 KB
• Volume: 29
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)80522-5

✦ Synopsis

Preferred conformations about c( and 8(1-6)-linkages of four types of 04,06branching trisaccharides I-IV were studied to examine the influence of the possible interaction between the g-4 and g-6 linked residues on the solution conformations.

In the course of our studies with chirally deuterated sugars, 1,2) C6-specifically deuterated hexoses') have been successfully used to determine the conformational properties ($, $, w angles, Fig. 1) about the CS-C6 bonds of hexoses 3-6) (w on the basis of JH5,&6proR and JH5,H-6proS

) and of (l-6)-linked disaccharides 7,8) (0, 9, 0 on the basis of DESERT,8) NOE, them% cal shifts of the H-6= and H-6& and the JH5 H6 values). Here, our method was applied to