Conformational alterations during biosynthesis of HLA-DR3 molecules controlled by invariant chain and HLA-DM

Frequency of abnormal expression of HLA-

Frequency of abnormal expression of HLA-A,B,C and HLA-DR molecules, invariant chain, and LFA-3 (CD58) in colorectal carcinoma and its impact on tumor recurrence

✍ Peter Möller; Karin Koretz; Peter Schlag; Frank Momburg 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 869 KB

HLA-A,B,C and HLA-DR molecules are involved in cognate LFA-3 (CD58) in antigen-independent T-celVtarget-cell interaction. T-cell-mediated host-versus-tumor response might therefore depend on the presence of both types of molecules on the surface of the target cell. To investigate whether presence or