Conformation of the transmembrane domain of the epidermal growth factor receptor
โ Scribed by Paul W. Brandt-Kauf; Regina Monaco; Matthew R. Pincus
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 454 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1573-4943
No coin nor oath required. For personal study only.
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The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-termi