✦ LIBER ✦
Conformation of the oligonucleotide d(AAAAAATTTTTT)2 by two-dimensional nuclear overhauser effect spectroscopy and its relevance to poly(dA) · poly(dT)
✍ Scribed by Siddhartha Roy; Babul Borah; Gerald Zon; Jack S. Cohen
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1987
- Tongue
- English
- Weight
- 559 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
✦ Synopsis
Maryhnd20892
synopsis Conformational analysis from the pattern and intensities of cross-peaks in the two-dimensional nuclear Overhauser effect proton nmr spectra of the homopolymer, poly(dA) . poly(dT), and the analogous oligomer, d(AAAAAAITITIT),, indicate that they both exist in the B-conformation. The conformation of the ApT/TpA junction in the oligomer is significantly different from the rest of the base pairs.