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Conformation of Prion Protein Repeat Peptides Probed by FRET Measurements and Molecular Dynamics Simulations

โœ Scribed by Gustiananda, Marsia; Liggins, John R.; Cummins, Peter L.; Gready, Jill E.

Book ID
118516095
Publisher
Biophysical Society
Year
2004
Tongue
English
Weight
279 KB
Volume
86
Category
Article
ISSN
0006-3495

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๐Ÿ“œ SIMILAR VOLUMES

Conformation of Prion Protein Repeat Pep
Conformation of Prion Protein Repeat Peptides Probed by FRET Measurements and Molecular Dynamics Simulations
โœ Gustiananda, Marsia; Liggins, John R.; Cummins, Peter L.; Gready, Jill E. ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Biophysical Society ๐ŸŒ English โš– 279 KB

We report the combined use of steady-state fluorescence resonance energy transfer (FRET) experiments and molecular dynamics (MD) simulations to investigate conformational distributions of the prion protein (PrP) repeat system. FRET was used for the first time to probe the distance, as a function of